In 1285, monastery papers mention the village by its current name for the first time. The terms Repanidion or Rapanidi appear in community papers from the 13th to the 16th centuries, and they appear again in the 19th century in the forms Repanidion, Rapanidi, Ropanidi, Repanidi, or Repanidi. As a result, the village’s name is most likely derived from the wild radish. The earliest occupants of Repanidi came from Iphaistia which had begun to be abandoned by its population around the 2nd century.

Athanasios, the new martyr, was born in Repanidi, which was conquered by the Turks in 1846 and he was sent to Constantinople by ship. The martyr, however, was never to reach the city since the guards chained him, then tossed him into the water and drowned him while sailing in the Hellespont, knowing that he would most likely be exonerated in the higher court because he had done no crime.

The importance of the Repanidi area has been recognised since ancient times, when the famous “Limnia Earth” was mined in the nearby region of Agiochoma.